目的 探討囊性腦膜瘤的磁共振表現、表觀彌散系數（ADC）圖的影像特點、ADC值與病理分級的關系及ADC值對判斷不同病理亞型腦膜瘤的價值。 方法 回顧性分析2003年3月－2007年12月18例經病理證實的囊性腦膜瘤患者的磁共振表現，其中男8例，女10例，平均年齡45.6歲。在ADC圖上分別測量腫瘤實質、瘤周水腫、囊變區的平均ADC值（均取4～6個區域，取平均值），比較不同病理亞型、不同病理分級的腫瘤實質、瘤周水腫、囊變區的ADC值差異是否有統計學意義。 結果 良惡性腦膜瘤腫瘤實質ADC值差異無統計學意義（P＞0.05）；囊性腦膜瘤各亞型間的腫瘤實質、瘤周水腫的ADC值差異無統計學意義（P＞0.05）；腫瘤實質、囊變區與瘤周水腫平均ADC值相比差異均有統計學意義（P＜0.05）。 結論 ADC值可區分腫瘤實質、囊變區及瘤周水腫，但對腦膜瘤亞型及良惡性的甄別需結合常規MRI與增強的征象。
Objective To explore the MRI imaging manifestation, features of apparent diffusion coefficient (ADC) map and the relationships among ADC value, pathologic grading and pathologic subtype of cystic meningioma. Methods The clinical data of 18 patients (8 males and 10 females, with an average age of 45.6 years) with cystic meningiomas confirmed by pathologically examination were retrospectively analyzed. The ADC values of tumor parenchyma, peritumoral edema, cystic regions and the contralateral normal brain of the tumor parenchyma were measured and analyzed.
The ADC value of the tumor parenchyma, peritumoral edema, cystic region were measured and then compared with the pathological findings. P value of less than 0.05 was considered as having a statistically significant difference. Results There was no significant difference in ADC values between benign and malignant meningioma and also among the tumor parenchyma, periedema and cystic region in different pathological subtypes. The difference in ADC values amongst tumor parenchyma, peritumoral edema and cystic region were statistically significant (P＜0.05). Conclusions Although ADC quantitative measurement allows the differentiation of the tumor parenchyma, cystic region and peri-edema, it is need to combined with conventional MR examination to assess tumor malignancy as well as grading in cystic meningioma.
引用本文： 邱麗華,韓福剛,朱建軍,曹躍勇,刁顯明,唐光才. 磁共振彌散加權成像在囊性腦膜瘤診斷中的應用. 華西醫學, 2012, 27(1): 44-50. doi: CNKI: 51-1356/R.20120115.1541.010 復制